Item Number：C3840
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Specification & Item NumberC3840-0500（500ml）； C3840-0050X10（50ml*10） ；C3840-0050（50ml）
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Storage Conditions-20ºC
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Conditions Carriagedry ice
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Validity Period (Months)60
Product Introduction
Low-fat fetal bovine serum removes endogenous lipids, triglycerides and cholesterol by solid matrix degreasing, and its content is only 1/3 of that of standard fetal bovine serum.
Fat-free fetal bovine serum is a natural medium which is widely used in cell culture. It contains rich nutrients necessary for cell growth, and is often used for in vitro culture of animal cells, which has extremely important functions.
1. Provide hormones for maintaining the exponential growth of cells, nutrients with little or no amount in the basic medium and main low-molecular-weight nutrients.
2. Provide binding proteins that can recognize vitamins, lipids, metals and other hormones, and can bind or modulate the activity of the substances they bind.
3. In some cases, protein can combine with toxic metals and pyrogens to detoxify.
4. It is the source of factors needed for cells to adhere to the wall and spread on plastic culture medium.
5. It acts as a pH buffer.
6. Protease inhibitors are provided to inactivate the remaining trypsin during cell passage and protect cells from damage.
Fat-free fetal bovine serum is a natural medium which is widely used in cell culture. It contains rich nutrients necessary for cell growth, and is often used for in vitro culture of animal cells, which has extremely important functions.
1. Provide hormones for maintaining the exponential growth of cells, nutrients with little or no amount in the basic medium and main low-molecular-weight nutrients.
2. Provide binding proteins that can recognize vitamins, lipids, metals and other hormones, and can bind or modulate the activity of the substances they bind.
3. In some cases, protein can combine with toxic metals and pyrogens to detoxify.
4. It is the source of factors needed for cells to adhere to the wall and spread on plastic culture medium.
5. It acts as a pH buffer.
6. Protease inhibitors are provided to inactivate the remaining trypsin during cell passage and protect cells from damage.
Product Application
Fat-free fetal bovine serum can be used to study the correlation between protein kinase CK2-α' and lung metastasis of adenoid cystic carcinoma;
1. Protein kinase is the largest member of the enzyme family, which is used to catalyze protein phosphorylation, which is the most common mechanism to control cell life activities. One of the most effective protein kinases is probably CK2. CK2(protein kinase CK2, PKCK2) used to be called casein kinase -2 or Ⅱ. It is a heterogeneous tetramer composed of two catalytic subunits (aa') and two regulatory subunits (β β).
2. Protein kinase CK2 is composed of two aa'ββ-type heterodimers with 42-42—44KDa and 38KDa, respectively. The structure is very stable and can only be dissociated under denaturing conditions in vitro. In addition to the cell matrix, some viral proteins are also phosphorylated by CK2. Protein kinase CK2 plays a role in transcription, signaling, proliferation, and various cellular steps leading to tumorigenesis.
1. Protein kinase is the largest member of the enzyme family, which is used to catalyze protein phosphorylation, which is the most common mechanism to control cell life activities. One of the most effective protein kinases is probably CK2. CK2(protein kinase CK2, PKCK2) used to be called casein kinase -2 or Ⅱ. It is a heterogeneous tetramer composed of two catalytic subunits (aa') and two regulatory subunits (β β).
2. Protein kinase CK2 is composed of two aa'ββ-type heterodimers with 42-42—44KDa and 38KDa, respectively. The structure is very stable and can only be dissociated under denaturing conditions in vitro. In addition to the cell matrix, some viral proteins are also phosphorylated by CK2. Protein kinase CK2 plays a role in transcription, signaling, proliferation, and various cellular steps leading to tumorigenesis.
Production And Quality System
Manufactured under ISO 13485 QMS and in compliance with applicable cGMP guidelines.
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