MEM-α medium contains all 21 common amino acids and increases the concentration of some amino acids. In addition, it contains 5 vitamins, which is the most abundant version of MEM. Since vitamin C reacts with calcium ions to form crystals, vitamin C is removed from the original formula to reduce the adverse effects of cell culture caused by crystallization. SLE (Super low endotoxin) grade, endotoxin ≤ 0.1 EU/mL.

Harry Eagle has developed the Minimum Essential Medium (MEM) as one of the most widely used of all synthetic cell culture media.