• Widely used for complexing inhibitory heavy metals
• Cell culture tested
• Suitable for cell culture, molecular biology & biochemistry applications
• Long-term storage when handled properly under defined conditions

Product DescriptionEDTA is a polyaminocarboxylic acid (PACA) and organic chelating agent (i.e., from the Greek xnAí, chele, claw) used in many enzyme buffers and, at higher concentrations, as an enzyme inactivator. It is not only used in metal chelation, ion exchange, and antioxidation procedures but also in spectrophotometric titration and other chemical procedures. Its prominence as a chelating agent arises from its ability to sequester di- and tri-cationic metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution while exhibiting diminished capacity as they are extensively enveloped, and as consequence catalytic properties of enzymes are often suppressed. A chelate is a water-soluble complex between a metal ion and a complexing agent. If chelators are small molecules that bind very tightly to metal ions, then chelation is the process of binding or complexation of a bi- or multi-dentate ligand. As a member of the PACA family of ligands, EDTA usually binds to a metal cation forming multiple bonds through its two amines and four carboxylates.

Manufactured under ISO 13485 QMS and in compliance with applicable cGMP guidelines.