Item Number：C3450
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Specification & Item NumberC3450-0100 (100ml)；C3450-0020 (20ml)
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Storage Conditions-20ºC
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Conditions Carriagedry ice
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Validity Period (Months)24
Product Introduction
Gentamicin sulfate is an aminoglycoside (aminocyclitol) antibiotic isolated from Micromonospora purpurea and represents the products of secondary carbohydrate metabolism. They are a closely related group of bactericidal antibiotics and have broadly similar toxicological features. Gentamicin sulfate is an antimicrobial agent with bactericidal properties against Gram-negative, Gram-positive bacteria, and Mycoplasma spp. Its mode of action (MOA) includes its binding to the L-6 protein of the 50S ribosomal subunit, inhibiting translocation, eliciting miscoding, and thereby inhibiting protein synthesis and compromising the bacterial cell-wall/membrane structure and eventually causing bacterial cell death. The 2-deoxystreptamine-containing antibiotics include the structurally related neomycins and streptomycins.
Cross-resistance occurs between kanamycin, neomycin, paromomycin, and framycetin, and partial cross-resistance has been reported between kanamycin and streptomycin. The aminoglycosides are excellent at synergizing with the β-lactams and glycopeptides to improve the efficiency of their bactericidal activity. It is incompatible with amphotericin, penicillins, sodium bicarbonate, and other drugs.
Important Note: Please consult other comprehensive pharmacology references regarding other antibiotic properties, characteristics, interactions, and possible incompatibilities.
Some Predominant Characteristics include:
• Easy-to-use formulation
• Bactericidal activity
• Stable in solution
• Sterile-filtered
Cross-resistance occurs between kanamycin, neomycin, paromomycin, and framycetin, and partial cross-resistance has been reported between kanamycin and streptomycin. The aminoglycosides are excellent at synergizing with the β-lactams and glycopeptides to improve the efficiency of their bactericidal activity. It is incompatible with amphotericin, penicillins, sodium bicarbonate, and other drugs.
Important Note: Please consult other comprehensive pharmacology references regarding other antibiotic properties, characteristics, interactions, and possible incompatibilities.
Some Predominant Characteristics include:
• Easy-to-use formulation
• Bactericidal activity
• Stable in solution
• Sterile-filtered
Product Application
Gentamicin sulfate is an antimicrobial agent with bactericidal properties against Gram-negative, Gram-positive bacteria, and Mycoplasma spp.
Production And Quality System
Manufacturing in accordance with cGMP guidelines, in accordance with ISO13485 production standards.
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