Item Number：C3460
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Specification & Item NumberC3460-0100 (100ml)
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Storage Conditions-20ºC
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Conditions Carriagedry ice
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Validity Period (Months)12
Product Introduction
Kanamycin sulfate is an aminoglycoside (aminocyclitol) antibiotic isolated from Streptomyces kanamyceticus and represent a product of secondary carbohydrate metabolism. They are a closely related group of bactericidal antibiotics and have broadly similar toxicological features. Kanamycin sulfate is an antimicrobial agent with bactericidal properties against Gram-negative and Gram-positive bacteria and Mycoplasma spp. Its mode of action (MOA) includes binding to the 70S ribosomal subunit, inhibits translocation (i.e., part of the translation process in which mRNA is shifted one codon in relation to the ribosome) and elicits miscoding (i.e., causing mRNA to be misread by the ribosome) causing a lethal level of translational errors thereby inhibiting protein synthesis and a cascade effect resulting in bacterial cell death. The 2-deoxystreptamine-containing antibiotics include the structurally related neomycins and streptomycins.
Cross-resistance occurs between kanamycin, neomycin, paromomycin, and framycetin, and partial cross-resistance has been reported between kanamycin and streptomycin. The aminoglycosides are excellent at synergizing with β-lactams and glycopeptides to improve the efficiency of their bactericidal activity.
• Predominant Characteristics
• Easy-to-use formulation
• Isolated from Streptomyces kanamyceticus
• Bactericidal activity
• Frozen solution
• Sterile-filtered (0.1 µm)
Cross-resistance occurs between kanamycin, neomycin, paromomycin, and framycetin, and partial cross-resistance has been reported between kanamycin and streptomycin. The aminoglycosides are excellent at synergizing with β-lactams and glycopeptides to improve the efficiency of their bactericidal activity.
• Predominant Characteristics
• Easy-to-use formulation
• Isolated from Streptomyces kanamyceticus
• Bactericidal activity
• Frozen solution
• Sterile-filtered (0.1 µm)
Product Application
Kanamycin sulfate is an antimicrobial agent with bactericidal properties against Gram-negative and Gram-positive bacteria and Mycoplasma spp
Production And Quality System
Manufacturing in accordance with cGMP guidelines, in accordance with ISO13485 production standards.
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